Antiemetics are therapeutic agents which are used to treat vomiting and nausea caused by several medical conditions. Nausea and vomiting are not diseases, they are symptoms associated with a variety of medical conditions such as gastroenteritis, motion sickness, dizziness, pregnancy, overeating, emotional stress and food poisoning. Nausea is a condition of unease in the stomach with an involuntary desire to vomit, this often occurs before vomiting. Various antiemetics used to treat vomiting and nausea are dolasetron, olanzapine, alizapride, cyclizine, promethazine and lorazepam. Some of the commercially available brands of antiemetics are Phenergan (promethazine) by Baxter Healthcare Corporation and Zyprexa (olanzapine) by Eli Lilly.
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The market for antiemetics is segmented on the basis of different class of drugs used to treat emesis and nausea such as 5-HT3 receptor antagonists, dopamine antagonists, NK1 receptor antagonists, anticholinergics and others. 5HT3 receptor antagonists act by blocking serotonin receptors in the central nervous system and gastrointestinal tract and comprises of dolastron, ondansetron and tropistron. Dopamine antagonists include domperidone, olanzapine and alizapride while aprepitant and casopitant are NK1 receptor antagonists.
The market for antiemetic drugs is projected to grow worldwide under the influence of increasing incidences of cancer, increased number of surgical procedures being conducted worldwide and other diseases. As mentioned earlier nausea and vomiting are not diseases but they are symptoms and side effects of a variety of diseases including cancer, gastroenteritis, surgeries and early stages of pregnancy. The market of antiemetic drugs will experience along with the increasing incidences of the aforementioned diseases. Nausea is one of the major symptoms caused by motion sickness, if the motion responsible for nausea is not resolved, it will result into vomiting. Extensive travelling causing motion sickness is also one of the major factors driving the growth of the market. The market is growing the fastest in Asia-Pacific due to large number of patients suffering from cancer, gastroenteritis and other diseases causing nausea and vomiting.
Some of the market players in this industry are Pfizer, Baxter International, GlaxoSmithKline, Sanofi, Novartis AG, Merck & Co., Astellas Pharma, Inc., Eli Lilly, Johnson& Johnson, Bristol-Myers Squibb and others.
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- Asia Pacific
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